Copy Link
Add to Bookmark
Report
Pig Genome Newsletter #112
From: "Rothschild, Max F [AN S]" <mfrothsc@iastate.edu>
To: angenmap@animalgenome.org
Subject: US Pig Genome Newsletter #112
Date: Mon, 02 Jul 2012 08:11:30 -0500
Pig Genome Update # 112:
- PDF version is available at
http://www.animalgenome.org/pig/newsletter/pdf/No.112.pdf
- Web version is available at
http://www.animalgenome.org/pig/newsletter/No.112.html
- Plain text version is appended below:
P I G G E N O M E U P D A T E
_________________________________________________________________
A Periodic Newsletter of the U.S. Pig Genome Coordination Program
************** No. 112 **************
* *
* July 1, 2012 *
***************************************
===========================================================================
1. The Swine Genome Sequencing Consortium is pleased to announce that we
have reached another significant milestone
2. The International Society of Animal Genetics (ISAG) 2012 Conference is
around the corner
3. NRSP-8 rewrite is progressing well
4. SNP chip update
5. Upcoming meetings ( 5 items )
===========================================================================
The Swine Genome Sequencing Consortium is pleased to announce that we have
reached another significant milestone in the Pig Genome Project. We have
completed the manuscript describing the generation, analysis and annotation
of a high quality draft reference pig genome sequence. The manuscript has
been submitted for publication and is currently under review.
The manuscript entitled "Pig genomes provide insight into porcine
demography, domestication and evolution" describes not only the generation
and analysis of a high quality draft reference genome sequence of a single
domesticated pig (Sus scrofa) but also the analysis of 16 other individual
genomes including both 10 European and Asian wild boar (Sus scrofa) and 6
domesticated pigs. Amongst, the major farmed animal species the pig is
unique in as much as the wild ancestors (wild boar from Europe and Asia)
from which it was domesticated are still extant. The analyses provide new
insights into the demography of wild boar and their subsequent
domestication. For example, we have evidence of a deep phylogenetic split
between Asian and European wild boar which points to their divergence about
1 million years ago. Our analyses provide further insight in the
domestication of the pig in the past 10,000 years as well as the more recent
development of specific breeds.
Analysis of the pig genome and its gene content in an evolutionary context
has revealed accelerated evolution of genes associated with immune response
and olfaction. Olfaction is clearly important to this scavenging animal. The
pig is not only an important agricultural species (pork is the most widely
consumed meat globally) but also an important biomedical model. The 1000
Genomes project has revealed that humans carry a burden of potential loss of
function mutations. Analysis of individual pig genomes has revealed similar
mutations. These mutations potentially extend the scope of the pig as a
biomedical model. This manuscript represents the efforts of the Consortium
and the authors include scientists from over 50 laboratories in 12 different
countries. The Consortium is associated with a series of companion papers
of which 17 are currently under review, revision or in press in BMC journals
with a further 5-10 in draft (kindly provided by Alan Archibald on behalf of
the Swine Genome Sequencing Consortium).
o o o o o o o o o o o
The International Society of Animal Genetics (ISAG) 2012 Conference in
Cairns, Australia on July 15-20th is around the corner. They have an
exciting scientific program planned with excellent plenary speakers,
workshops and poster sessions, and of course, a truly outstanding
location. The theme of the ISAG 2012 conference is "Quantitative Genetics
Meets Molecular Genetics" and many of our plenary speakers will reflect
this theme. However, the plenary sessions will reflect also a wide variety
of other interesting and topical areas in genetics, including gene
expression defining phenotypes, ancient DNA analysis of livestock,
epigenetics and new technologies. The ISAG conference workshops and
symposia will include not only the genomics and DNA testing of specific
animal species (eg cattle, sheep, goats, birds, pigs, horses, dogs, cats,
fish), but there will be also dedicated workshops on animal genome
sequencing, immunogenetics, forensics, genetic diversity, epigenetics and
comparative genomics. For more information, please see:
http://www.isag.us/2012. Please join us for a fantastic conference.
Provided by Cindy Bottema on behalf of the 33rd ISAG Organizing Committee.
o o o o o o o o o o o
NRSP-8 rewrite is progressing well. The NRSP-8 is scheduled to end in
September of 2013, so if it is to continue, it must be revised and
resubmitted for review by NIFA and the Experiment Stations again this year.
The approximate deadline is this September for submitting the revised
project. New draft objectives for NRSP-8 and a draft have been circulated.
All members of NRSP-8 may receive requests for input into the new proposals.
Please respond promptly, as we're on a tight deadline and this will be a
huge help to the writing teams. A special thanks to Tom Porter and the
writing team for leading this effort.
o o o o o o o o o o o
SNP chip update. An Illumina low density SNP panel is currently in
production through GeneSeek Inc. The chip will include close to 10,000 SNP
and will be available around the end of August (kindly provided by Jeremy
Walker).
o o o o o o o o o o o
Upcoming meetings (see:
http://www.animalgenome.org/pigs/community/meetings.html)
33rd International Society for Animal Genetics Conference in Cairns,
Australia on July.15-20, 2012. For details see http://www.isag.us/2012/
American Society of Animal Science (ASAS), Dairy Science (ADSA), and
Canadian Society of Animal Science (CSA) Joint Annual Meeting in Phoenix,
AZ on July 15 - 19, 2012. For details see http://www.jtmtg.org/2012/
PAG-XXI/NRSP-8 will be January 12-16, 2013, for details see
http://www.intlpag.org/web/
Gordon Research Conferences: Quantitative Genetics & Genomics, Genetics
of Complex Disease, February 17-22, 2013, Galveston, TX for details see
http://www.grc.org/programs.aspx?year=2013&program=quantgen
PAG Asia to be held in Singapore, March 2013. For details see
http://www.intlpag.org/web
<> <> <> <> <> <> <> <> <> <> <>
Items for Pig Genome Update 113 can be sent to me by no later than September 15
please.
Max Rothschild
U.S. Pig Genome Coordinator
2255 Kildee Hall,
Department of Animal Science
Iowa State University
Ames, Iowa 50011
Phone: 515-294-6202
Fax: 515-294-2401
mfrothsc@iastate.edu
http://www.animalgenome.org/pig/
===========================================================================
Supported by Multi-State Research Funds to the National Research Service
Program: NRSP-8. National Animal Genome Research Program, Muquarrab Qureshi,
NAGRP Director, NIFA
---------------------------------------------------------------------------
Web: http://www.animalgenome.org/pig | Mail: angenmap@animalgenome.org
===========================================================================
