PiHKAL: The Chemical Story 10
@eZine
Published in
PiHKAL
· 1 year ago
... no activity being found with MEDA, all was abandoned. There are some comments made under MDA for successful chemistry (using a different approach) alo#ng these lines when there is no methoxyl group present. These are the compounds EDA and IDA. But the pharmacology was still not that exciting. #121 MEE; 4,5-DIETHOXY-2-METHOXYAMPHETAMINE SYNTHESIS: To a solution of 166 g bourbonal in 1 L MeOH there was added a solution of 66 g KOH pellets in 300 mL H2O. There was then added 120 g ethyl bromide, and the mixture was held at reflux on the steam bath for 3 h. The reaction was quenched with three volumes of H2O, and made strongly basic by the addition ...